Interrogation of Phenotypic Plasticity between Epithelial and Mesenchymal States in Breast Cancer

Interrogation of Phenotypic Plasticity between Epithelial and Mesenchymal States in Breast Cancer

Dynamic interconversions between transitional epithelial and mesenchymal states underpin the epithelial mesenchymal plasticity (EMP) seen in some carcinoma cell systems. We have delineated epithelial and mesenchymal subpopulations existing within the PMC42-LA breast cancer cell line by their EpCAM e...

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Bibliographic Details
Main Authors: Sugandha Bhatia, James Monkman, Tony Blick, Cletus Pinto, Mark Waltham, Shivashankar H Nagaraj, Erik W Thompson
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Journal of Clinical Medicine
Subjects:
copy number variations (CNV)
epithelial-mesenchymal transition (EMT)
intratumoral heterogeneity
mesenchymal-epithelial transition (MET)
phenotypic plasticity
single cell-derived clones
whole exome sequencing
Online Access:https://www.mdpi.com/2077-0383/8/6/893

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https://www.mdpi.com/2077-0383/8/6/893

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