Suppression of fatty acid synthase promoter by polyunsaturated fatty acids

Dietary polyunsaturated fat is known to suppress expression of fatty acid synthase (FAS), a central enzyme in de novo lipogenesis. The sterol regulatory element-binding protein (SREBP) has recently been shown to be involved in this suppression. We previously reported that the first 2.1 kb of the FAS...

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Bibliographic Details
Main Authors: Yang Soo Moon, Maria-Jesus Latasa, Michael J. Griffin, Hei Sook Sul
Format: Article
Language:English
Published: Elsevier 2002-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301103