Suppression of fatty acid synthase promoter by polyunsaturated fatty acids
Dietary polyunsaturated fat is known to suppress expression of fatty acid synthase (FAS), a central enzyme in de novo lipogenesis. The sterol regulatory element-binding protein (SREBP) has recently been shown to be involved in this suppression. We previously reported that the first 2.1 kb of the FAS...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2002-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520301103 |