Long-Term Follow-Up and Optimization of Interleukin-1 Inhibitors in the Management of Monogenic Autoinflammatory Diseases: Real-Life Data from the JIR Cohort

Long-Term Follow-Up and Optimization of Interleukin-1 Inhibitors in the Management of Monogenic Autoinflammatory Diseases: Real-Life Data from the JIR Cohort

Objectives: The major role of interleukin (IL)-1 in the pathogenesis of hereditary recurrent fever syndromes favored the employment of targeted therapies modulating IL-1 signaling. However the best use of IL1 inhibitors in terms of dosage is difficult to define at present.Methods: In order to better...

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Bibliographic Details
Main Authors: Véronique Hentgen, Isabelle Koné-Paut, Alexandre Belot, Caroline Galeotti, Gilles Grateau, Aurelia Carbasse, Anne Pagnier, Pascal Pillet, Marc Delord, Michael Hofer, Sophie Georgin-Lavialle
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
anakinra
canakinumab
cryopyrin-associated periodic syndrome
Tumor Necrosis factor (TNF)-receptor-associated periodic syndrome
mevalonate kinase deficiency
posology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.568865/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.568865/full

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