Role of MCM2–7 protein phosphorylation in human cancer cells

Abstract A heterohexameric complex composed of minichromosome maintenance protein 2–7 (MCM2–7), which acts as a key replicative enzyme in eukaryotes, is crucial for initiating DNA synthesis only once per cell cycle. The MCM complex remains inactive through the G1 phase, until the S phase, when it is...

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Bibliographic Details
Main Authors: Liangru Fei, Hongtao Xu
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cell & Bioscience
Subjects:
MCM
Online Access:http://link.springer.com/article/10.1186/s13578-018-0242-2