CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

Chronic viral infections are frequently associated with the dysfunction of CD8+ T cells which includes loss of function and results in CD8+ T cell exhaustion. Here the authors show a role of CEACAM1 in promoting responsive CD8+ T cells in the context of a chronic lymphocytic choriomeningitis virus (...

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Bibliographic Details
Main Authors: Vishal Khairnar, Vikas Duhan, Ashwini M. Patil, Fan Zhou, Hilal Bhat, Christine Thoens, Piyush Sharma, Tom Adomati, Sarah-Kim Friendrich, Judith Bezgovsek, Janine D. Dreesen, Gunther Wennemuth, Astrid M. Westendorf, Gennadiy Zelinskyy, Ulf Dittmer, Cornelia Hardt, Jörg Timm, Joachim R. Göthert, Philipp A. Lang, Bernhard B. Singer, Karl S. Lang
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04832-2

Internet

https://doi.org/10.1038/s41467-018-04832-2

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