Identifying Cancers Impacted by CDK8/19

Identifying Cancers Impacted by CDK8/19

CDK8 and CDK19 Mediator kinases are transcriptional co-regulators implicated in several types of cancer. Small-molecule CDK8/19 inhibitors have recently entered or are entering clinical trials, starting with breast cancer and acute myeloid leukemia (AML). To identify other cancers where these novel...

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Bibliographic Details
Main Authors: Igor B. Roninson, Balázs Győrffy, Zachary T. Mack, Alexander A. Shtil, Michael S. Shtutman, Mengqian Chen, Eugenia V. Broude
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
CDK8
CDK19
Cyclin C
cancer genomics
survival correlations
Online Access:https://www.mdpi.com/2073-4409/8/8/821

Internet

https://www.mdpi.com/2073-4409/8/8/821

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