Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex

Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is associated with neurodevelopmental abnormalities, including defects in neuronal migration. However, the alterations in cell signaling mechanisms critical for migration and final positioning of neurons in TSC remain unclear. Our detailed cellular analyses reveal th...

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Bibliographic Details
Main Authors: Uk Yeol Moon, Jun Young Park, Raehee Park, Jennifer Y. Cho, Lucinda J. Hughes, James McKenna III, Laura Goetzl, Seo-Hee Cho, Peter B. Crino, Michael J. Gambello, Seonhee Kim
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715007536

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http://www.sciencedirect.com/science/article/pii/S2211124715007536

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