The Kaleidoscope of Microglial Phenotypes

The Kaleidoscope of Microglial Phenotypes

Gene expression analyses of microglia, the tissue-resident macrophages of the central nervous system (CNS), led to the identification of homeostatic as well as neurological disease-specific gene signatures of microglial phenotypes. Upon alterations in the neural microenvironment, either caused by lo...

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Bibliographic Details
Main Authors: Marissa L. Dubbelaar, Laura Kracht, Bart J. L. Eggen, Erik W. G. M. Boddeke
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
microglia
activation
phenotype
transcriptome
neurodegenerative diseases
core gene signature
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01753/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01753/full

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