Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic flux.

Epigallocatechin gallate (EGCG) is a major polyphenol in green tea with beneficial effects on the impairment in learning and memory. Autophagy is a cellular process that protects neurons from stressful conditions. The present study was designed to investigate whether EGCG can rescue chronic unpredic...

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Bibliographic Details
Main Authors: Hong-Feng Gu, Ya-Xiong Nie, Qiao-Zhen Tong, Ya-Ling Tang, Yang Zeng, Kai-Quan Jing, Xi-Long Zheng, Duan-Fang Liao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4231069?pdf=render