Maternal Choline and Betaine Supplementation Modifies the Placental Response to Hyperglycemia in Mice and Human Trophoblasts
Gestational diabetes mellitus (GDM) is characterized by excessive placental fat and glucose transport, resulting in fetal overgrowth. Earlier we demonstrated that maternal choline supplementation normalizes fetal growth in GDM mice at mid-gestation. In this study, we further assess how choline and i...
Main Authors: | Khatia Nanobashvili, Chauntelle Jack-Roberts, Rachel Bretter, Naudia Jones, Kathleen Axen, Anjana Saxena, Kali Blain, Xinyin Jiang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
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Series: | Nutrients |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6643/10/10/1507 |
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