Simultaneous Determination of Five Phenolic Acids and Four Flavonoid Glycosides in Rat Plasma Using HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Intravenous Administration of Kudiezi Injection

Simultaneous Determination of Five Phenolic Acids and Four Flavonoid Glycosides in Rat Plasma Using HPLC-MS/MS and Its Application to a Pharmacokinetic Study after a Single Intravenous Administration of Kudiezi Injection

This study has developed a reliable and precise high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of five phenolic acids and four flavonoid glycosides in rat plasma after a single intravenous administration of Kudiezi injection (KI). Chromatogr...

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Bibliographic Details
Main Authors: Peiying Shi, Chunlei Yang, Ya Su, Liying Huang, Xinhua Lin, Hong Yao
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
high performance liquid chromatography-tandem mass spectrometry
phenolic acids
flavonoid glycosides
pharmacokinetics
Kudiezi injection
Online Access:http://www.mdpi.com/1420-3049/24/1/64

Internet

http://www.mdpi.com/1420-3049/24/1/64

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