Individual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis

Individual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis

Abstract Background Patients with pneumococcal meningitis are at risk for death and neurological sequelae including cognitive impairment. Functional genetic polymorphisms of macrophage migration inhibitory factor (MIF) alleles have shown to predict mortality of pneumococcal meningitis. Methods We in...

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Bibliographic Details
Main Authors: Anne T. Kloek, Mercedes Valls Seron, Ben Schmand, Michael W. T. Tanck, Arie van der Ende, Matthijs C. Brouwer, Diederik van de Beek
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Acta Neuropathologica Communications
Subjects:
Macrophage migration inhibitory factor
Bacterial meningitis
Pneumococcal meningitis
Cognitive impairment
Online Access:https://doi.org/10.1186/s40478-020-01100-7

Internet

https://doi.org/10.1186/s40478-020-01100-7

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