ParticleCall: A particle filter for base calling in next-generation sequencing systems

<p>Abstract</p> <p>Background</p> <p>Next-generation sequencing systems are capable of rapid and cost-effective DNA sequencing, thus enabling routine sequencing tasks and taking us one step closer to personalized medicine. Accuracy and lengths of their reads, however, a...

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Bibliographic Details
Main Authors: Shen Xiaohu, Vikalo Haris
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/160