The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders

The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders

Abstract Many neurodegenerative disorders, including Parkinson’s, Alzheimer’s, and amyotrophic lateral sclerosis, are well known to involve the accumulation of disease-specific proteins. Less well known are the accumulations of another set of proteins, neuronal intermediate filaments (NFs), which ha...

Full description

Bibliographic Details
Main Authors: Alessandro Didonna, Puneet Opal
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Neurodegeneration
Subjects:
Neurofilaments
Protein aggregation
Protein degradation
Neurodegeneration
Giant axonal neuropathy (GAN)
Charcot-Marie-tooth (CMT) disease
Online Access:http://link.springer.com/article/10.1186/s13024-019-0318-4

Internet

http://link.springer.com/article/10.1186/s13024-019-0318-4

Similar Items