Dendrobium officinale polysaccharide attenuates type 2 diabetes mellitus via the regulation of PI3K/Akt-mediated glycogen synthesis and glucose metabolism

Dendrobium officinale polysaccharide attenuates type 2 diabetes mellitus via the regulation of PI3K/Akt-mediated glycogen synthesis and glucose metabolism

This study aimed to explore the therapeutic effects of Dendrobium officinale polysaccharide (DOP), an active ingredient isolated from the water extract of Dendrobium officinale, in streptozotocin (STZ)-induced type 2 diabetic BALB/c mice and its potential mechanisms. Our results showed that DOP had...

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Bibliographic Details
Main Authors: Kaiping Wang, Hanxiang Wang, Yage Liu, Weizhi Shui, Junfeng Wang, Peng Cao, Hongjing Wang, Ruxu You, Yu Zhang
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Functional Foods
Subjects:
Dendrobium officinale
Polysaccharide
Glucose metabolism
Glycogen synthesis
Glucose metabolism enzymes
PI3K/Akt signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461730676X

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http://www.sciencedirect.com/science/article/pii/S175646461730676X

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