Parathyroid Hormone Causes Endothelial Dysfunction by Inducing Mitochondrial ROS and Specific Oxidative Signal Transduction Modifications

Parathyroid Hormone Causes Endothelial Dysfunction by Inducing Mitochondrial ROS and Specific Oxidative Signal Transduction Modifications

Vitamin D deficiency contributes to cardiovascular risk (CVR), with hyperparathyroidism advocated as a putative mechanism. Indeed, mounting evidence supports the hypothesis that parathyroid hormone (PTH) impairs endothelial function, even though mechanisms are not fully elucidated. The present study...

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Bibliographic Details
Main Authors: Jessica Gambardella, Matteo De Rosa, Daniela Sorriento, Nella Prevete, Antonella Fiordelisi, Michele Ciccarelli, Bruno Trimarco, Nicola De Luca, Guido Iaccarino
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/9582319

Internet

http://dx.doi.org/10.1155/2018/9582319

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