KRAS mutation analysis by PCR: a comparison of two methods.

BACKGROUND:KRAS mutation assays are important companion diagnostic tests to guide anti-EGFR antibody treatment of metastatic colorectal cancer. Direct comparison of newer diagnostic methods with existing methods is an important part of validation of any new technique. In this this study, we have com...

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Bibliographic Details
Main Authors: Louise Bolton, Anne Reiman, Katie Lucas, Judith Timms, Ian A Cree
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4287618?pdf=render