Peripheral blood mononuclear cells derived from grand multigravidae display a distinct cytokine profile in response to P. falciparum infected erythrocytes.

Peripheral blood mononuclear cells derived from grand multigravidae display a distinct cytokine profile in response to P. falciparum infected erythrocytes.

Immunopathology of placental malaria is most significant in women in their first pregnancy especially in endemic areas, due to a lack of protective immunity to Plasmodium falciparum, which is acquired in successive pregnancies. In some studies (but not all), grand multigravidae (defined as 5 or more...

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Bibliographic Details
Main Authors: Louise E Ludlow, Wina Hasang, Alexandra J Umbers, Emily K Forbes, Maria Ome, Holger W Unger, Ivo Mueller, Peter M Siba, Anthony Jaworowski, Stephen J Rogerson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3899203?pdf=render

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http://europepmc.org/articles/PMC3899203?pdf=render

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