All-trans retinoic acid inhibits lipopolysaccharide-induced inflammatory responses in bovine adipocytes via TGFβ1/Smad3 signaling pathway

All-trans retinoic acid inhibits lipopolysaccharide-induced inflammatory responses in bovine adipocytes via TGFβ1/Smad3 signaling pathway

Abstract Background Dairy cows with metabolic disorder in peripartal period display high inflammatory levels. Adipose tissue is a major endocrine organ, which is closely related to systemic inflammation. Retinoic acid (RA), an active metabolite of vitamin A, has shown potential therapeutic immunomod...

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Bibliographic Details
Main Authors: Qiushi Xu, Hongdou Jia, Li Ma, Guowen Liu, Chuang Xu, Ying Li, Xinwei Li, Xiaobing Li
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Veterinary Research
Subjects:
All-trans retinoic acid
TGFβ1/Smad3 signaling
Bovine adipocytes
Inflammatory responses
Online Access:http://link.springer.com/article/10.1186/s12917-019-1791-2

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http://link.springer.com/article/10.1186/s12917-019-1791-2

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