Lactamomethylation of alkylphenols: Synthesis and quantum-chemical study of the reaction pathway

Six novel lactamomethyl derivatives of 2,5-dimethylphenol and 2,3,5-trimethylphenol were prepared with moderate yields by the reaction of corresponding phenols with 1-(hydroxymethyl)lactams in the presence of an acid catalyst. In all cases, the substitution occurred at position 4 to the phenolic hyd...

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Bibliographic Details
Main Authors: Stepan V. Vorobyev, Olga V. Primerova, Sergey Yu. Bylikin, Vladimir N. Koshelev
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221004391