Efficacy of CMX001 as a Post Exposure Antiviral in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

Efficacy of CMX001 as a Post Exposure Antiviral in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

CMX001, a lipophilic nucleotide analog formed by covalently linking 3-(hexdecyloxy)propan-1-ol to cidofovir (CDV), is being developed as a treatment for smallpox. In the absence of human cases of smallpox, new treatments must be tested for efficacy in animal models. Previously, we demonstrated the e...

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Bibliographic Details
Main Authors: Scott Foster, Randall Lanier, Alice Robertson, Richard W. Moyer, George Painter, Bernhard Lampert, Brandi R. Manning, Stacey A. Gray, Daniele Swetnam, Andrew J. Smith, Mathew M. Adams, Greg Wallace, Scott F. Lindsey, Andrew M. Burrage, Amanda D. Rice
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Viruses
Subjects:
poxvirus
antiviral
CMX001
rabbitpox
smallpox treatment
Online Access:http://www.mdpi.com/1999-4915/3/1/47/

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http://www.mdpi.com/1999-4915/3/1/47/

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