Expression and Immunogenicity of M2e Peptide of Avian Influenza Virus H5N1 Fused to Ricin Toxin B Chain Produced in Duckweed Plants

Expression and Immunogenicity of M2e Peptide of Avian Influenza Virus H5N1 Fused to Ricin Toxin B Chain Produced in Duckweed Plants

The amino acid sequence of the extracellular domain of the virus-encoded M2 matrix protein (peptide M2e) is conserved among all subtypes of influenza A strains, enabling the development of a broad-range vaccine against them. We expressed M2e from avian influenza virus A/chicken/Kurgan/5/2005 (H5N1)...

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Bibliographic Details
Main Authors: Aleksey Firsov, Irina Tarasenko, Tatiana Mitiouchkina, Lyubov Shaloiko, Oleg Kozlov, Leonid Vinokurov, Ekaterina Rasskazova, Arkadii Murashev, Alexander Vainstein, Sergey Dolgov
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Chemistry
Subjects:
duckweed
avian influenza
peptide M2e
ricin B subunit
mice immunization
edible vaccine
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2018.00022/full

Internet

http://journal.frontiersin.org/article/10.3389/fchem.2018.00022/full

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