Lack of Galectin-3 Disrupts Thymus Homeostasis in Association to Increase of Local and Systemic Glucocorticoid Levels and Steroidogenic Machinery

Lack of Galectin-3 Disrupts Thymus Homeostasis in Association to Increase of Local and Systemic Glucocorticoid Levels and Steroidogenic Machinery

Maintenance of thymus homeostasis is a delicate interplay involving hormones, neurotransmitters and local microenvironmental proteins, as well as saccharides, acting on both thymocytes and stromal cells. Disturbances in these interactions may lead to alterations on thymocyte development. We previous...

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Bibliographic Details
Main Authors: Ednéa Oliveira-de-Abreu, Danielle Silva-dos-Santos, Ailin Lepletier, Tiago D. P. Ramos, Rafaella Ferreira-Reis, Larissa Vasconcelos-Fontes, Mariana T. Ramos, Rafael C. Torres, Vinícius Cotta-de-Almeida, Vinícius de Frias Carvalho, Déa M. S. Villa-Verde
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
galectin-3
thymus
thymocytes
proliferation
cell death
glucocorticoid
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00365/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00365/full

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