Mechanisms and determinants of ultralong action potential duration and slow rate-dependence in cardiac myocytes.

In normal cardiac myocytes, the action potential duration (APD) is several hundred milliseconds. However, experimental studies showed that under certain conditions, APD could be excessively long (or ultralong), up to several seconds. Unlike the normal APD, the ultralong APD increases sensitively wit...

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Bibliographic Details
Main Authors: Zhilin Qu, Douglas Chung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3428352?pdf=render