EH Domain-Containing 2 Deficiency Restricts Adipose Tissue Expansion and Impairs Lipolysis in Primary Inguinal Adipocytes

EH Domain-Containing 2 Deficiency Restricts Adipose Tissue Expansion and Impairs Lipolysis in Primary Inguinal Adipocytes

Lipid uptake can be facilitated via caveolae, specific plasma membrane invaginations abundantly expressed in adipocytes. The dynamin-related protein EH domain-containing 2 (EHD2) stabilizes caveolae at the cell surface. Here, we have examined the importance of EHD2 for lipid handling using primary a...

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Bibliographic Details
Main Authors: Claes Fryklund, Björn Morén, Shrenika Shah, Mario Grossi, Eva Degerman, Claudia Matthaeus, Karin G. Stenkula
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
adipocytes
EH domain-containing 2
caveolae
fatty acids
adipose tissue
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.740666/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.740666/full

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