Levels of Cortisol in CSF Are Associated With SNAP-25 and Tau Pathology but Not Amyloid-β

Levels of Cortisol in CSF Are Associated With SNAP-25 and Tau Pathology but Not Amyloid-β

Objective: Preclinical studies have found both hyperactivity of hypothalamic- pituitary- adrenal (HPA) axis and synaptic degeneration are involved in the pathogenesis of Alzheimer’s disease (AD). However, the data on the relationship of activity of HPA axis and synaptic degeneration in humans are li...

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Bibliographic Details
Main Authors: Qing Wang, Wenjun Zhou, Jie Zhang, The Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
cortisol
SNAP-25
Alzheimer’s disease
tau pathology
synapse degeneration
mild cognitive impairment
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00383/full

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00383/full

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