Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity

Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity

Abstract Background Defective phagocytosis in alveolar macrophages is associated with chronic obstructive pulmonary disease (COPD). Transient receptor potential cation channel subfamily V member 2 (TRPV2), a type of nonselective cation channel pertinent to diverse physiological functions, regulates...

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Bibliographic Details
Main Authors: Hiroaki Masubuchi, Manabu Ueno, Toshitaka Maeno, Koichi Yamaguchi, Kenichiro Hara, Hiroaki Sunaga, Hiroki Matsui, Masahiro Nagasawa, Itaru Kojima, Yuko Iwata, Shigeo Wakabayashi, Masahiko Kurabayashi
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Pulmonary Medicine
Subjects:
Alveolar macrophage
Chronic obstructive pulmonary disease (COPD)
Cigarette smoke
Phagocytosis
Transient receptor potential V2 (TRPV2)
Online Access:http://link.springer.com/article/10.1186/s12890-019-0821-y

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http://link.springer.com/article/10.1186/s12890-019-0821-y

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