Decreased dicer expression enhances SRP-mediated protein targeting.

We have shown that Dicer processes 7SL RNA into different fragments ranging from ∼20 to more than 200 nucleotides. Here we addressed the molecular functions of these 7SL RNA fragments and found that some of them functioned as dominant-negative regulators of the full-length 7SL RNA, interfering with...

Full description

Bibliographic Details
Main Authors: Yong-Feng Ren, Guiling Li, Yong-Feng Xue, Xue-Jiao Zhang, Yi-Jiang Song, Lu Lv, Jianmin Wu, Yu-Xiao Fang, Yu-Qun Wang, Ke-Qing Shi, Yong-Ping Chen, Kai-Fu Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585229?pdf=render