Decreased dicer expression enhances SRP-mediated protein targeting.
We have shown that Dicer processes 7SL RNA into different fragments ranging from ∼20 to more than 200 nucleotides. Here we addressed the molecular functions of these 7SL RNA fragments and found that some of them functioned as dominant-negative regulators of the full-length 7SL RNA, interfering with...
Main Authors: | Yong-Feng Ren, Guiling Li, Yong-Feng Xue, Xue-Jiao Zhang, Yi-Jiang Song, Lu Lv, Jianmin Wu, Yu-Xiao Fang, Yu-Qun Wang, Ke-Qing Shi, Yong-Ping Chen, Kai-Fu Tang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3585229?pdf=render |
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