A fine-structure map of spontaneous mitotic crossovers in the yeast Saccharomyces cerevisiae.

Homologous recombination is an important mechanism for the repair of DNA damage in mitotically dividing cells. Mitotic crossovers between homologues with heterozygous alleles can produce two homozygous daughter cells (loss of heterozygosity), whereas crossovers between repeated genes on non-homologo...

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Bibliographic Details
Main Authors: Phoebe S Lee, Patricia W Greenwell, Margaret Dominska, Malgorzata Gawel, Monica Hamilton, Thomas D Petes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2646836?pdf=render