Structure-templated predictions of novel protein interactions from sequence information.

The multitude of functions performed in the cell are largely controlled by a set of carefully orchestrated protein interactions often facilitated by specific binding of conserved domains in the interacting proteins. Interacting domains commonly exhibit distinct binding specificity to short and conse...

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Bibliographic Details
Main Authors: Doron Betel, Kevin E Breitkreuz, Ruth Isserlin, Danielle Dewar-Darch, Mike Tyers, Christopher W V Hogue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1988853?pdf=render