hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway

Abstract The period circadian regulator 3 (PER3) has been reported to play a negative role in human immortalized bone marrow-derived Scp-1 cells (iBMSCs) and patient adipose-derived stromal cells (PASCs) or a negative/positive role in mice adipogenesis. However, human PER3 (hPER3) was identified as...

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Bibliographic Details
Main Authors: Xinxing Wan, Liyong Zhu, Liling Zhao, Lin Peng, Jing Xiong, Wenjun Yang, Jingjing Yuan, Fang Liang, Keke Zhang, Ke Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03584-0