Adipose tissue protects against sepsis-induced muscle weakness in mice: from lipolysis to ketones

Adipose tissue protects against sepsis-induced muscle weakness in mice: from lipolysis to ketones

Abstract Background ICU-acquired weakness is a debilitating consequence of prolonged critical illness that is associated with poor outcome. Recently, premorbid obesity has been shown to protect against such illness-induced muscle wasting and weakness. Here, we hypothesized that this protection was d...

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Bibliographic Details
Main Authors: Chloë Goossens, Ruben Weckx, Sarah Derde, Thomas Dufour, Sarah Vander Perre, Lies Pauwels, Steven E. Thiessen, Paul P. Van Veldhoven, Greet Van den Berghe, Lies Langouche
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Critical Care
Subjects:
Adipose tissue
Skeletal muscle
Sepsis
Metabolism
Muscle weakness
Online Access:http://link.springer.com/article/10.1186/s13054-019-2506-6

Internet

http://link.springer.com/article/10.1186/s13054-019-2506-6

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