The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts

The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts

Abstract Background Reversible cell cycle arrest (quiescence/G0) is characteristic of adult stem cells and is actively controlled at multiple levels. Quiescent cells also extend a primary cilium, which functions as a signaling hub. Primary cilia have been shown to be important in multiple developmen...

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Bibliographic Details
Main Authors: Nisha Venugopal, Ananga Ghosh, Hardik Gala, Ajoy Aloysius, Neha Vyas, Jyotsna Dhawan
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Molecular and Cell Biology
Subjects:
Quiescence
Myoblasts
G0
Primary cilium
Signaling
Online Access:http://link.springer.com/article/10.1186/s12860-020-00266-1

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http://link.springer.com/article/10.1186/s12860-020-00266-1

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