Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin
Photocaged molecules have advantages in terms of temporal and spatial control compared to conventional pharmacological compounds. The authors present a synthetic saxitoxin derivative affixed to a photocleavable group for precise modulation of Na channels.
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-24392-2 |