Optimization of Novel Naproxen-Loaded Chitosan/Carrageenan Nanocarrier-Based Gel for Topical Delivery: Ex Vivo, Histopathological, and In Vivo Evaluation

Optimization of Novel Naproxen-Loaded Chitosan/Carrageenan Nanocarrier-Based Gel for Topical Delivery: Ex Vivo, Histopathological, and In Vivo Evaluation

Naproxen (NAP) is commonly used for pain, inflammation, and stiffness associated with arthritis. However, systemic administration is linked with several gastrointestinal tract (GIT) side effects. The present work aims to prepare and evaluate NAP nanoparticulate shells of chitosan (CS) and carrageena...

Full description

Bibliographic Details
Main Authors: Sobia Noreen, Fahad Pervaiz, Akram Ashames, Manal Buabeid, Khairi Fahelelbom, Hina Shoukat, Irsah Maqbool, Ghulam Murtaza
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceuticals
Subjects:
chitosan
carrageenan
anti-inflammatory
naproxen
polyelectrolyte complexation
nanocarriers
Online Access:https://www.mdpi.com/1424-8247/14/6/557

Internet

https://www.mdpi.com/1424-8247/14/6/557

Similar Items