Targeting the non-structural protein 1 from dengue virus to a dendritic cell population confers protective immunity to lethal virus challenge.

Dengue is the most prevalent arboviral infection, affecting millions of people every year. Attempts to control such infection are being made, and the development of a vaccine is a World Health Organization priority. Among the proteins being tested as vaccine candidates in preclinical settings is the...

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Bibliographic Details
Main Authors: Hugo R Henriques, Eline V Rampazo, Antonio J S Gonçalves, Elaine C M Vicentin, Jaime H Amorim, Raquel H Panatieri, Kelly N S Amorim, Marcio M Yamamoto, Luís C S Ferreira, Ada M B Alves, Silvia B Boscardin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3715404?pdf=render