Metabolic engineering of Escherichia coli for shikimate pathway derivative production from glucose–xylose co-substrate

In lignocellulose biomass, microbes prefer consuming glucose over xylose, which affects target compound production. Here, the authors achieve simultaneous utilization of glucose and xylose for target chemical production and cell growth, respectively, and realize high-level production of shikimate pa...

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Bibliographic Details
Main Authors: Ryosuke Fujiwara, Shuhei Noda, Tsutomu Tanaka, Akihiko Kondo
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-14024-1