mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV

mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV

Abstract Background The mechanistic target of rapamycin (mTOR) pathway is a potential target to inhibit pathologic processes in choroidal neovascularization. However, the exact role of mTOR signaling in the development of CNV remains obscure. In this study, we assessed the role of mTORC1 and mTORC2...

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Bibliographic Details
Main Authors: Jin Young Yang, Sanjar Batirovich Madrakhimov, Dong Hyuck Ahn, Hun Soo Chang, Sang Joon Jung, Seung Kwan Nah, Ha Yan Park, Tae Kwann Park
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cell Communication and Signaling
Subjects:
Age-related macular degeneration
Choroidal neovascularization
Sirolimus (rapamycin)
mTORC1
mTORC2
Online Access:http://link.springer.com/article/10.1186/s12964-019-0380-0

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http://link.springer.com/article/10.1186/s12964-019-0380-0

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