BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data.

BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data.

Activation of CD4+ T cells requires the recognition of peptides that are presented by HLA class II molecules and can be assessed experimentally using the ELISpot assay. However, even given an individual's HLA class II genotype, identifying which class II molecule is responsible for a positive E...

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Bibliographic Details
Main Authors: Lies Boelen, Patrick K O'Neill, Kathryn J Quigley, Catherine J Reynolds, Bernard Maillere, John H Robinson, Ganjana Lertmemongkolchai, Daniel M Altmann, Rosemary J Boyton, Becca Asquith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004796

Internet

https://doi.org/10.1371/journal.pcbi.1004796

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