Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination

Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination

Several human diseases are associated with a lack of caveolae. Yet, the functions of caveolae and the molecular mechanisms critical for shaping them still are debated. We show that muscle cells of syndapin III KO mice show severe reductions of caveolae reminiscent of human caveolinopathies. Yet, dif...

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Bibliographic Details
Main Authors: Eric Seemann, Minxuan Sun, Sarah Krueger, Jessica Tröger, Wenya Hou, Natja Haag, Susann Schüler, Martin Westermann, Christian A Huebner, Bernd Romeike, Michael M Kessels, Britta Qualmann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
caveolar invagination
nanodomains
ultrastructural analyses of membrane topologies
mechanical stress
caveolinopathies
Online Access:https://elifesciences.org/articles/29854

Internet

https://elifesciences.org/articles/29854

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