Targeted Activation of T Cells with IL-2-Coupled Nanoparticles

Interleukin-2 (IL-2) is a T cell growth factor particularly required in regulatory T cell maintenance and memory T cell responses. High-dose IL-2 treatment was the first FDA-approved immunotherapy for cancer, while low-dose IL-2 administration has shown promise in allograft rejection and autoimmune...

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Bibliographic Details
Main Authors: Verena K. Raker, Christian Becker, Katharina Landfester, Kerstin Steinbrink
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/9/2063