Suppression of lymphocyte apoptosis in spleen by CXCL13 after porcine circovirus type 2 infection and regulatory mechanism of CXCL13 expression in pigs

Abstract Porcine circovirus-associated disease (PCVAD) is one of the most serious infectious diseases in pigs worldwide. The primary causative agent of PCVAD is porcine circovirus type 2 (PCV2), which can cause lymphoid depletion and immunosuppression in pigs. Our previous study demonstrated that La...

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Bibliographic Details
Main Authors: Gen Liu, Yanchao Wang, Shijin Jiang, Minmin Sui, Changying Wang, Li Kang, Yi Sun, Yunliang Jiang
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-019-0634-2