Cattle Immunized with a Recombinant Subunit Vaccine Formulation Exhibits a Trend towards Protection against Histophilus somni Bacterial Challenge.

Histophilosis, a mucosal and septicemic infection of cattle is caused by the Gram negative pathogen Histophilus somni (H. somni). As existing vaccines against H. somni infection have shown to be of limited efficacy, we used a reverse vaccinology approach to identify new vaccine candidates. Three gro...

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Bibliographic Details
Main Authors: Claudia Avis Madampage, Don Wilson, Hugh Townsend, Gordon Crockford, Neil Rawlyk, Donna Dent, Brock Evans, Joyce Van Donkersgoed, Craig Dorin, Andrew Potter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4976985?pdf=render