Structure, Activity and Function of the MLL2 (KMT2B) Protein Lysine Methyltransferase

The Mixed Lineage Leukemia 2 (MLL2) protein, also known as KMT2B, belongs to the family of mammalian histone H3 lysine 4 (H3K4) methyltransferases. It is a large protein of 2715 amino acids, widely expressed in adult human tissues and a paralog of the MLL1 protein. MLL2 contains a characteristic C-t...

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Bibliographic Details
Main Authors: Alexia Klonou, Sarantis Chlamydas, Christina Piperi
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/8/823