Antinociceptive Activity of Methanolic Extract of Clinacanthus nutans Leaves: Possible Mechanisms of Action Involved

Methanolic extract of Clinacanthus nutans Lindau leaves (MECN) has been proven to possess antinociceptive activity that works via the opioid and NO-dependent/cGMP-independent pathways. In the present study, we aimed to further determine the possible mechanisms of antinociception of MECN using variou...

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Bibliographic Details
Main Authors: Zainul Amiruddin Zakaria, Mohammad Hafiz Abdul Rahim, Rushduddin Al Jufri Roosli, Mohd Hijaz Mohd Sani, Maizatul Hasyima Omar, Siti Farah Mohd. Tohid, Fezah Othman, Siew Mooi Ching, Arifah Abdul Kadir
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2018/9536406