Evaluation of the selectivity of G-quadruplex ligands in living cells with a small molecule fluorescent probe

G-quadruplex has been an emerging target for drug design due to its physiologically important roles in oncology. A number of quadruplex-interactive ligands have been developed by synthetic and medicinal chemists over the past decades. However, the great challenge still remains that the method for de...

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Bibliographic Details
Main Authors: Suge Zhang, Hongxia Sun, Dawei Yang, Yan Liu, Xiufeng Zhang, Hongbo Chen, Qian Li, Aijiao Guan, Yalin Tang
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Analytica Chimica Acta: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590134619300131