Antioxidant and Cardioprotective Effects of EPA on Early Low-Severity Sepsis through UCP3 and SIRT3 Upholding of the Mitochondrial Redox Potential

Antioxidant and Cardioprotective Effects of EPA on Early Low-Severity Sepsis through UCP3 and SIRT3 Upholding of the Mitochondrial Redox Potential

Sepsis still causes death, often through cardiac failure and mitochondrial dysfunction. Dietary ω3 polyunsaturated fatty acids are known to protect against cardiac dysfunction and sepsis lethality. This study set out to determine whether early low-severity sepsis alters the cardiac mitochondrial fun...

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Bibliographic Details
Main Authors: Thibault Leger, Kasra Azarnoush, Amidou Traoré, Lucie Cassagnes, Jean-Paul Rigaudière, Chrystèle Jouve, Guilhem Pagès, Damien Bouvier, Vincent Sapin, Bruno Pereira, Jean-Marie Bonny, Luc Demaison
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/9710352

Internet

http://dx.doi.org/10.1155/2019/9710352

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