DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice

Abstract Background Peroxisome proliferator-activated receptor alpha (PPARα) is associated with diabetic retinopathy (DR), and the underlying mechanism is still unclear. Aim of this work was to investigate the mechanism of PPARα in DR. Methods Human retinal capillary pericytes (HRCPs) were treated w...

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Bibliographic Details
Main Authors: Ying Zhu, Xinru Wang, Xiaoyun Zhou, Lexi Ding, Dan Liu, Huizhuo Xu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Biological Research
Subjects:
Online Access:https://doi.org/10.1186/s40659-021-00347-1