Indexing <it>TNF-α </it>gene expression using a gene-targeted reporter cell line

<p>Abstract</p> <p>Background</p> <p>Current cell-based drug screening technologies utilize randomly integrated reporter genes to index transcriptional activity of an endogenous gene of interest. In this context, reporter expression is controlled by known genetic elemen...

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Bibliographic Details
Main Authors: Engelhardt John F, Lei-Butters Diana, Yan Ziying, Leno Gregory H
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/7/8